UIC Pharmacy Blog

Information and tips for your health and wellness from UIC Pharmacy

Thursday, May 12, 2016

May is Mental Health Month

What is Mental Health?

What is mental health?
Mental health encompasses many aspects of our overall health and well-being and is made up of emotional, psychological, and social components.1 Emotion well-being refers to how satisfied an individual is with their current life situation, happiness, and peacefulness. Psychological well-being includes components such as self-acceptance, personal growth, openness to new experiences, optimism, and self-direction. An individual’s social well-being includes social acceptance, personal self-worth in society, and sense of community. Our mental health plays an integral role in how we function on a day-to-day basis and impacts our thoughts, feelings, and actions. It can also determine how we handle certain situations and has an impact on our personal relationships. Mental illness refers more specifically to a diagnosable mental disorder.2 Common mental illnesses include anxiety disorders, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, eating disorders, mood disorders, personality disorders, and schizophrenia. Depression is the most common mental illness, affecting more than a quarter of the U.S. adult population.

When to see your doctor or mental health provider.
Although it may be difficult to recognize when something is impacting your mental health, there are a few signs that may suggest it is time to have a discussion with your doctor or a mental health provider.3

Mood: Mood swings from feelings of “highs” to feelings of “lows” may be a sign of poor mental health. Also, persistent feelings of sadness, depression, or irritability lasting beyond two weeks may be an indication that it is time to speak with your healthcare provider about your mental health. Feeling more tense, nervous, or anxious than usual are also signs of many mental health concerns. Other changes in mood could include the inability to cope with daily problems or stress, feelings of guilt, or excessive anger, hostility, or violence.

Loss of interest or pleasure: A recent loss of interest or pleasure in activities, hobbies, or work that you once enjoyed is a common sign that you may need to discuss your mental health with your doctor. You may also find that it is more difficult to complete tasks or assignments in an efficient manner. Withdrawal from friends and family can also signify a significant mental health problem.

Appetite: Changes in eating habits such as eating too much or too little may indicate that it is time for a mental health checkup. Craving certain types of foods that are high in fat or sugar is also a stress response that could result in lower levels of energy and could have an even more negative result on your mood. A significant amount of weight loss without attempting to lose weight or a significant weight gain could be diagnostic of a mental health problem.

Sleep: Recent changes in sleep patterns or habits may also signify a problem with your current mental health. When faced with higher amounts of stress, people often respond with having trouble either falling asleep or staying asleep throughout the night. The quality of sleep could also be impacted and you may find yourself waking up without feeling re-energized. In comparison to not being able to sleep well at night, sleeping more than the normal amount of 7 to 9 hours per night can also be a symptom of a mental health problem.

Feeling of restlessness or being slowed down: You may feel that you are unable to sit still and must always be up moving. You could also experience feeling shaking or have unusual movements. By contrast, you could also feel slowed down and not able to move as quickly or as graceful as you normally would.

Energy: Along with problems getting the appropriate amount of sleep each night, feelings of not having enough energy to get through the day are also common with many mental health problems. Many patients with depression or anxiety issues complain of feelings of significant fatigue and low energy and are not able to complete things that they either must do or want to do.

Concentration: Many mental health issues can contribute to an individual’s ability to focus and concentrate. You can recognize your ability to concentrate by noticing if your productivity levels have decreased, if you’re unable to make deadlines, or if you’re unable to complete simple daily tasks such as housework. You may also find that you are unable to make appropriate decisions in a timely manner.

Physical symptoms: some mental health illnesses may manifest with physical symptoms such as stomach pain, back pain, headaches, and other general body aches and pain.

Preparing for your first visit.
Experiencing even just a few of these signs and symptoms is a reason to see your doctor or a mental health provider, especially if they are interfering with your ability to function on a day-to-day basis. You may choose to discuss your mental health concerns with your primary care doctor or you may go directly to a mental health provider, such as a psychiatrist or psychologist. In preparation for your first appointment, you should think about a number of questions that your doctor may ask you. These include:

When did you first notice your symptoms?
Has your day-to-day life been affected by your symptoms?
What have you tried to treat your symptoms on your own?  
Do you notice anything that makes you feel worse? Do your symptoms have a specific trigger?
Have your friends or family members commented on your mood?
Does mental illness run in your family?
What do you expect from treatment?
What medications, supplements, or herbs to you currently take?
Do you drink alcohol or use illegal (street) drugs?

It is important for you to think about the types of questions you should ask your doctor or other mental health provider prior to your first appointment. Examples of the types of questions to ask your doctor include:

What type of treatment will I receive?
Will counseling or therapy help?
Are there medications that will help?
How long will it take for my treatment to start working?
Is there anything I can do on my own to help myself?
Do you have any brochures that I can have to read?

Suicide Prevention.
If you feel that you are in a crisis or having thoughts of killing yourself please call the Suicide Prevention Lifeline at 1-800-273-TALK (1-800-273-8255) immediately. The Suicide Prevention Lifeline is a 24-hour service available to anyone in need of help.

Where to find more information.
If you would like to find out more about mental health or mental illness, below are a few helpful resources:
American Psychological Association: http://www.apa.org/
National Institute of Mental Health: http://www.nimh.nih.gov/index.shtml
American Psychiatric Association: http://www.psychiatry.org/mental-health
Mental Health America: http://www.mentalhealthamerica.net/
National Alliance on Mental Illness: http://www.nami.org/

Maggie Thomas
Doctor of Pharmacy Candidate
College of Pharmacy, University of Illinois at Chicago
UIC Pharmacy
November 2013

References
1.     What is mental health? U.S. Department of Health and Human Services.http://www.mentalhealth.gov/basics/what-is-mental-health/index.html. Accessed November 12, 2013.
2.     Mental health. National Institute of Mental Health.http://www.nimh.nih.gov/health/publications/depression/index.shtml. Accessed November 12, 2013.
3.     Warning signs of mental illness. American Psychiatric Association.http://www.psychiatry.org/mental-health/more-topics/warning-signs-of-mental-illness.Accessed November 12, 2013.

Tuesday, April 12, 2016

Irritable Bowel Syndrome Awareness Month

Irritable bowel syndrome (IBS)
Stan Nikitin
April is IBS month, and you may be wondering “what exactly is IBS?” IBS stands for irritable bowel syndrome, which is a disorder affecting the large intestine, also called the colon.  It's one of the most commonly diagnosed gastrointestinal conditions, affecting 55 million Americans.  This means about 1 in 6 people have symptoms of IBS!  Women tend to be affected more often than men. The exact cause of IBS is unknown. There are many hypotheses and the causes may include genetics, problems with the intestinal muscles, infections, stress or other psychological factors.1-3

Symptoms of IBS
The symptoms of IBS usually begin in adolescence or early adulthood, but can occur at any age.  Symptoms can vary in severity, but the good news is that most people with IBS have mild symptoms. Abdominal pain, fullness, flatulence (gas), and bloating that have been present for at least 6 months are the main symptoms of IBS.2  While different people are affected differently, the symptoms can also include:
·       Cramping - pain or tightness in the abdomen
·       Changes in bowel movements
·       Constipation or diarrhea - both can occur, but mostly it is one or the other
·       Mucus in the stool4
Symptoms are more likely to occur after meals, can come and go, and may be milder or disappear completely following a bowel movement.
All people are affected differently. For most people IBS is a chronic condition, but symptoms can come and go, improve or worsen, and be present constantly or intermittently.

The symptoms of IBS may seem daunting and scary, but fortunately, do not cause any permanent damage to the colon. For example, IBS does not increase the risk for colorectal cancer. Also, IBS does not cause any inflammation or changes in bowel tissue unlike the more serious intestinal diseases such as Crohn’s disease or ulcerative colitis.4


DiagnosisIBS is largely diagnosed based on symptoms.  Your doctor will diagnose IBS based on your symptoms, medical history, and a physical exam.  If any tests are necessary, they are to rule out any other conditions.  The tests may be necessary especially if there is weight loss, rectal bleeding, fever, nausea or recurrent vomiting, abdominal pain that is not completely relieved by a bowel movement, diarrhea that is persistent or awakens you from sleep, or if symptom onset occurs after the age of 50.  Some of the tests can include:4
·       Blood tests - check for blood loss or deficiency, inflammation, and Celiac disease (symptoms of which may resemble IBS)
·       Stool analysis - checks for blood in the stool and certain infections (for example, parasites).
·       Sigmoidoscopy or colonoscopy - allows the doctor to look inside the intestine for abnormal growths, bleeding, inflammation, and other irregularities
·       Lactose intolerance test - tests for lactase deficiency. Some people lack the enzyme lactase, which breaks down dairy sugars. Affected people may have symptoms resembling IBS after eating or drinking dairy products. Your doctor may instruct you to avoid dairy products for several weeks to rule out lactase deficiency.

TreatmentWhile IBS is a chronic condition, it is manageable. The focus of treatment is to relieve symptoms. Diet and lifestyle changes can help you manage IBS. More severe forms of IBS may require the use of medications that can help alleviate symptoms.


Diet and Lifestyle ChangesMaking changes to your diet and lifestyle may help relieve IBS symptoms.
Lifestyle changes:
·       Exercise - exercise may reduce anxiety and stress, which in turn may help relieve IBS symptoms.
·       Improved sleep habits – an erratic sleep schedule may worsen IBS symptoms. Improving your sleep habits may help. Try to go to bed at the same time each day and get plenty of sleep to avoid fatigue and potential stress.
Dietary changes:
·       Eat at regular times - try to eat at the same time each day. Do not skip meals. Avoid large meals.
·       Avoid problem foods - avoid foods that you know for certain trigger your IBS symptoms. Avoid fatty foods or ones with high sugar content. Artificial sweeteners (such as sorbitol and mannitol) may be found in sugar-free gum or other foods and can be problematic. Certain foods and drinks stimulate the intestines. Caffeine containing products (coffee, tea, and energy drinks) are notorious for this effect. Carbonated drinks like soda can produce gas. Some other problem foods may include whole grains, chocolate, or alcohol. Vegetables like broccoli, cauliflower, cabbage, and beans can increase gas. Dairy products may cause much discomfort to lactose intolerant people. See lactose intolerance test above.1,2,4
·       Foods rich in fiber - while fiber-rich foods such as fruits, vegetables, and beans may help with constipation for some people, they can make symptoms worse for others.
·       Drink plenty of water - water is always best. Remember that coffee, tea, alcohol, soda, and dairy products like milk can worsen the symptoms.
MedicationMedication use in IBS should target your most upsetting symptoms. The lowest dose possible that relieves your symptoms is usually recommended. If you are considering using over-the-counter medication, discuss such use with your doctor or pharmacist before selecting one. Explaining your symptoms to your doctor or pharmacist can help the healthcare professional recommend the right medication for you.
Over-the-counter (OTC) medications
·       Immodium (loperamide) - loperamide decreases the frequency of bowel movements, which may be of relief to some with diarrhea, but it does not help with other IBS symptoms.
·       Fiber supplements - fiber supplements such as Metamucil may help with constipation- predominant IBS, but can make symptoms worse for people with diarrhea-predominant IBS.
·       Laxatives - there are various laxative types that work in different ways to help with constipation.  Discuss with your doctor or pharmacist which laxative may be appropriate for you.
Prescription medications
Diarrhea-Predominant IBS:
·       Antispasmodic drugs may help with intestinal spasms and cramping.2-5 These drugs relax the smooth muscles of the intestine using an anticholinergic mechanism. Some examples of these medications are hyoscyamine and dicyclomine.  Common side effects are drowsiness, dry mouth, blurred vision, constipation, and urinary retention.6
·       Cholestyramine may be helpful to people with bile acid absorption problems.1,3  The mostcommon side effect reported with cholestyramine use is constipation.6
·       Lotronex (alosetron) is approved for women only with diarrhea-predominant IBS and has restricted use. It can only be prescribed by a doctor enrolled in a special program.1,4,5  The most common side effect reported is constipation.6
Constipation Predominant IBS:
·       Amitiza (lubiprostone) is approved for women 18 and older only who have constipation predominant IBS. 4, 5 Common side effects are nausea, headache, and diarrhea.6
Other therapies:
·       Xifaxan (rifaximin) is an oral non-absorbable (acts in the gastrointestinal tract without getting into the bloodstream) antibiotic that may be effective for global IBS symptoms, especially for diarrhea-predominant IBS. 7 This drug is minimally absorbed and stays in the intestine. Common side effects are flatulence (gas), nausea, dizziness, and fatigue.6
·       For difficult to treat conditions your doctor may prescribe antidepressants. These can include 2 drug classes: tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs). These can be helpful in relieving abdominal pain and slowing down intestinal transit time.1,2,4,5 Common side effects with TCAs are drowsiness, dry mouth, blurred vision, constipation, urinary retention, and weight gain.6  Common side effects with SSRIs are headache, sleepiness, insomnia, nausea, diarrhea, and sexual dysfunction.6
·       Other treatment options exist such as probiotics, peppermint oil, herbal therapies and acupuncture. While these treatments may be helpful and beneficial to some, there’s little medical evidence about their effectiveness.

What to expect
Irritable bowel syndrome can be a chronic, lifelong condition and has no known cure. Many people with IBS learn to manage the condition and still lead active, fruitful lives. Understandably, the condition may not be easy to discuss, but be open about your communication with healthcare professionals. Be informed, ask lots of questions, and remember that healthcare professionals are there to help! Be your own advocate and take charge in the management of your IBS!
For more information:
·       Mayo Clinic 
http://www.mayoclinic.com/health/irritable-bowel-syndrome/DS00106
·       WebMD
http://www.webmd.com/ibs/default.htm
·       WebMD Support Group Message Board
http://exchanges.webmd.com/ibs-support-group
·       National Institutes of Health
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001292
·       U.S. National Library of Medicine Interactive Tutorialhttp://www.nlm.nih.gov/medlineplus/tutorials/irritablebowelsyndrome/htm/index.htm
·       National Digestive Diseases Information Clearinghouse http://digestive.niddk.nih.gov/ddiseases/pubs/ibs/
·       American College of Gastroenterology
http://www.acg.gi.org/patients/ibsrelief/index.asp
References
1. Spruill WJ, Wade WE. Diarrhea, constipation, and irritable bowel syndrome. In: DiPiro JT, Talbert RL, Yee G, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach. 7th ed. New York, NY: McGraw-Hill; 2008:628-631.2. U.S. National Library of Medicine, National Institutes of Health. Irritable bowel syndrome. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001292. Updated July 7, 2010. Accessed February 24, 2011.

3. WebMD. Irritable bowel syndrome health center. http://www.webmd.com/ibs/default.htm. Updated May 23, 2008. Accessed February 24, 2011.

4. Mayo Clinic. Irritable bowel syndrome. http://www.mayoclinic.com/health/irritable-bowel-syndrome/DS00106. Updated July 29, 2009. Accessed February 24, 2011.

5. Wald, A. Treatment of irritable bowel syndrome. In: UpToDate, Talley NJ (Ed), UpToDate, Waltham, MA, 2011. Accessed February 24, 2011.6. Wickersham RM, ed. Drug Facts and Comparisons. St. Louis, MO: Wolters Kluwer Health; 2011. http://online.factsandcomparisons.com. Accessed March 2, 2011.
7. American College of Gastroenterology. ACG releases evidence-based systematic review on management of irritable bowel syndrome. http://www.acg.gi.org/media/releases/december182008.asp. Published December 18, 2008. Accessed March 14, 2011.