UIC Pharmacy Blog

Information and tips for your health and wellness from UIC Pharmacy

Monday, February 21, 2011

National Eating Disorders Awareness Week

February 20 - 26th is National Eating Disorders Awareness Week.  One of the most common eating disorders is Anorexia Nervosa (AN). AN is a serious and complex medical and psychiatric illness.1 It is not a personal choice with a simple solution. The disorder is a multifaceted problem that involves biological, genetic, social, cultural, familial, relational, and psychological factors.2 Patients suffering from AN may be oblivious to their unhealthy behaviors. Their body image mimics what we might see in a fun-house mirror. Despite evidence to the contrary, they still see an overweight individual staring back at them.3

While AN affects mostly girls and young women, it also affects older individuals, both female and male, and crosses racial, ethnic, and economic backgrounds.2 Anorexia does not always start as a clear cut disorder. It can start gradually with a new diet and exercise routine and develop into an unhealthy desire to lose weight that causes the individual to completely stop eating.3 That being said, anorexia is NOT dieting. A diet is a healthy desire to lose weight to improve health and appearance, while AN is a serious medical and psychiatric illness characterized by a distorted body image and an intense fear of gaining weight.1 Self-starvation and calorie restriction can be a way for anorexics to feel in control at a time in their life when things seem out of control. People with AN may also associate their ability to restrict calories and intake with feelings of self-worth and self-esteem. Unfortunately, these self-destructive behaviors do not address the underlying problems and can lead to greater emotional pain, isolation, and physical damage.2

Characteristics of anorexia:1-4
• A refusal to maintain a normal body weight for his or her height
• Making him- or herself throw up
• Taking pills to urinate or have a bowel movement (diuretics or laxatives) or diet pills
• Unhealthy eating habits: not eating, eating very little, weighing food and counting calories, eating very small amounts of only certain foods, moving food around the plate instead of eating it, complaints of feeling full even after eating very little
• Inappropriate exercise: even in bad weather or when hurt, tired, or sick
• Physical changes: weakness, lethargy, muscle loss, amenorrhea (loss of menses), delayed sexual development, edema, delayed gastric emptying, constipation, low heart rate and blood pressure, osteoporosis, dry cracking skin, lanugo (fine, downy body hair growth all over the body), feeling cold all the time, dizziness, faintness, and headaches

Anorexia causes many detrimental effects to the body.2 Patients with anorexia continuously starve themselves, leading to malnutrition. In a state of malnutrition, the body essentially feeds on itself for nutrients and slows down to conserve energy. To the left is a diagram of the health consequences of AN. As you can see, AN affects almost every part of the body. Left untreated, more than 5% to 10% of patients with AN die.4

Recovery from AN is possible.2 If you, a friend, or family member suffer from anorexia, it is important to seek help from a health professional. Depending on the severity of the condition, AN may be treated in the hospital, with regular visits to the doctor, or a combination of the two.1 The road to recovery involves both physical and psychological therapy.2

Goals of treatment:1-4
• Reduce distorted body image
• Restore and maintain a healthy body weight
• Reduce or eliminate behaviors or thoughts that lead to unhealthy eating habits
• Establish and maintain normal eating patterns
• Treat the psychological issues related to the eating disorder
• Resolve contributory family problems
• Prevent relapse

Treatment initially focuses on restoring a healthy weight and eliminating food phobias.4 When the patient is medically stable, treatment becomes directed towards cognitive behavioral therapy (CBT), interpersonal psychotherapy, and nutritional counseling. These treatments are focused on finding and maintaining a positive body image and developing healthy coping strategies. Data supporting the use of drugs to treat anorexia is limited. Antidepressants, such as fluoxetine (Prozac®), can be used if depression, anxiety, obsessions, or compulsions exist after the person has achieved a healthy body weight. Treatment with risperidone (Risperdal®) or olanzapine (Zyprexa®), atypical antipsychotics, has shown some benefit in increasing weight and reducing anxiety and depressive symptoms. Lorazepam (Ativan®) and alprazolam (Xanax®) have been used before meals to reduce severe anxiety that can limit eating. Lastly, metoclopramide (Reglan®) can be used to reduce common gastrointestinal symptoms of AN (e.g. bloating, premature fullness, and abdominal pain). These therapies should only be initiated under close supervision of a medical professional.

Written by Katie Williams and edited by Irene Hong, PharmD 


Remember, anorexia is a serious, life-threatening condition. Below is a list of organizations you can contact if you need help or more information.

UIC Students: UIC Counseling Center
• Phone: 1-312-996-3490
• Crisis Hotline: 1-312-996-5535 (every evening from 6 to 10:30)
• Internet Address: http://www.vcsa.uic.edu/MainSite/departments/counseling_center/home/

The National Eating Disorder Association:
• Toll-free Hotline: 1-800-931-2237
• Internet Address: http://www.nationaleatingdisorders.org

National Association of Anorexia Nervosa and Associated Disorders
• Helpline: 1-630-577-1330
• Phone: 1-847-831-3438
• Internet Address: http://www.anad.org

U.S. Department of Health and Human Services, Office on Women’s Health
• Phone: 1-800-994-9662
• Internet Address: www.womenshealth.gov

National Mental Health Information Center, SAMHSA, HHS
• Phone: 1-800-789-2647
• Internet Address: http://mentalhealth.samhsa.gov

National Institute of Mental Health (NIMH), NIH, HHS
• Phone: 1-866-615-NIMH (6464)
• Internet Address: http://www.nimh.nih.gov

Academy for Eating Disorders
• Phone: 1-847-498-4274
• Internet Address: http://www.aedweb.org

References:
1. The National Eating Disorders Association. The National Eating Disorders Association educator tool kit. http://www.nationaleatingdisorders.org/uploads/file/toolkits/NEDA-Toolkit-Educators_09-15-08.pdf. Updated 2008. Accessed Feb 26, 2010.
2. The National Women's Health Information Center. Anorexia Nervosa. http://www.womenshealth.gov/faq/anorexia-nervosa.cfm. Updated 2009. Accessed Feb 15, 2010.
3. National Institute of Mental Health. Anorexia Nervosa. http://www.nimh.nih.gov/health/publications/eating-disorders/anorexia-nervosa.shtml. Updated 2009. Accessed Feb 28, 2010.
4. Stoner SC. Eating disorders. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach. 7th ed. New York, NY: The McGraw-Hill Companies; 2008. http://www.accesspharmacy.com/content.aspx?aID=3194063. Accessed Feb 22 2010.

Monday, February 7, 2011

Cough and Cold Season Basics


Cold and Cough season is here again and we get a lot of questions about what products to use. So I just want to take a minute to end confusion at the Pharmacy and go over what to use with what type of sickness. I put this in a bullet point format so you can easily use it as a reference. Lastly, remember to please consult your UIC Pharmacist, we’re always ready to help with any questions you may have!

First off Nonprescription (OTC) medications are available to treat cold symptoms, but there are differences between them:

·      Over-the-counter Medications

·      Choose your remedy by determining which symptoms you want to treat
    • Stuffy nose – use a decongestant (e.g. Sudafed or Afrin)
    • Runny nose/watery eyes – use an antihistamine (e.g. Claritin)
    • Headache/aches and pains – use an analgesic (e.g. Tylenol)
    • Dry hacking cough – use an antitussive (e.g. dextromethorphan)
    • Multiple symptoms – use a combination product but be sure the product treats only the symptoms you have

·      Pediatric Use:  FDA has banned the use of cold and cough products in infants and children less than 2 years of age because serious side effects can occur

·      FDA is currently evaluating the use of these products in children 2-11 years of age; manufacturers have voluntarily agreed to cold and cough products with the warning “do not use in children under 4”

·      A recent study in the medical journal, “Chest” describes a single case report and animal studies using Vicks VapoRub.  The case reports describes a grandparent using VapoRub on a child less than 2 and under the nose, neither of which is appropriate use of the medication.  This highlights the importance of reading the label and following the directions on all over the counter medicines.  VapoRub is safe when used as directed.

Next I’ll take each medicine described above (decongestant, antihistamine, etc….) and break them down further.

·      Decongestants

·      Oral and topical products are available
·      Topical decongestants work the fastest and include products like Afrin but you can’t use them for more than 3 days
·      Oral decongestants include pseudoephedrine and phenylephrine products; pseudoephedrine products are found behind the pharmacy counter; it is worth asking for them as the duration of action is longer and the products can be more effective

·      Antihistamines

·       There are many antihistamines available but non-sedating product are generally your best choice. 
·       If you take a sedating antihistamine like Benadyl, be sure to carefully read labels for precautions such as ‘marked drowsiness may occur’ and ‘be careful when driving a motor vehicle’ and heed those warnings.  

·       Anelgesics

·      There are several choices for pain relief available.  Just about everybody can use Tylenol.  If you don’t have problems with ulcers or bleeding, Motrin or Aleve are other choices for pain relief.

·      Antitussives

·      Antitussives like dextromethorphan, which is in Vicks 44 or Delsym, can help stop dry, hacking, nonproductive coughs. 
·      You can also use diphenhydramine but it will cause drowsiness.

·      Combination Products

·       Products like Dimetapp, Actifed and others contain more than one active ingredient.  Be sure you are not taking anything else containing those ingredients or class of ingredients and that you have all of the symptoms listed on the label.

·      In Order To Get The Most From Your Non-Prescription Cold Medicines

·      Read the label, be sure you are not taking multiple products (Rx or OTC) containing the same ingredient (for example, some cold products and some products for insomnia contain the exact same active ingredients (diphenhydramine and/or acetaminophen); by taking them together, you are double dosing and can have side effects)
·      Follow the directions.
·      If you have questions, ask your pharmacist

Hope this helps you maneuver through Cold and Cough season!


Jan Engle, Pharm.D., FAPhA
Professor and Head, Department of Pharmacy Practice
Executive Associate Dean
UIC College of Pharmacy
Past President, American Pharmacists Association