May is Mental Health Month

What is Mental Health?

What is mental health?

Mental health encompasses many aspects of our overall health and well-being and is made up of emotional, psychological, and social components.¹ Emotion well-being refers to how satisfied an individual is with their current life situation, happiness, and peacefulness. Psychological well-being includes components such as self-acceptance, personal growth, openness to new experiences, optimism, and self-direction. An individual’s social well-being includes social acceptance, personal self-worth in society, and sense of community. Our mental health plays an integral role in how we function on a day-to-day basis and impacts our thoughts, feelings, and actions. It can also determine how we handle certain situations and has an impact on our personal relationships. Mental illness refers more specifically to a diagnosable mental disorder.² Common mental illnesses include anxiety disorders, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, eating disorders, mood disorders, personality disorders, and schizophrenia. Depression is the most common mental illness, affecting more than a quarter of the U.S. adult population.

When to see your doctor or mental health provider.

Although it may be difficult to recognize when something is impacting your mental health, there are a few signs that may suggest it is time to have a discussion with your doctor or a mental health provider.³

Mood: Mood swings from feelings of “highs” to feelings of “lows” may be a sign of poor mental health. Also, persistent feelings of sadness, depression, or irritability lasting beyond two weeks may be an indication that it is time to speak with your healthcare provider about your mental health. Feeling more tense, nervous, or anxious than usual are also signs of many mental health concerns. Other changes in mood could include the inability to cope with daily problems or stress, feelings of guilt, or excessive anger, hostility, or violence.

Loss of interest or pleasure: A recent loss of interest or pleasure in activities, hobbies, or work that you once enjoyed is a common sign that you may need to discuss your mental health with your doctor. You may also find that it is more difficult to complete tasks or assignments in an efficient manner. Withdrawal from friends and family can also signify a significant mental health problem.

Appetite: Changes in eating habits such as eating too much or too little may indicate that it is time for a mental health checkup. Craving certain types of foods that are high in fat or sugar is also a stress response that could result in lower levels of energy and could have an even more negative result on your mood. A significant amount of weight loss without attempting to lose weight or a significant weight gain could be diagnostic of a mental health problem.

Sleep: Recent changes in sleep patterns or habits may also signify a problem with your current mental health. When faced with higher amounts of stress, people often respond with having trouble either falling asleep or staying asleep throughout the night. The quality of sleep could also be impacted and you may find yourself waking up without feeling re-energized. In comparison to not being able to sleep well at night, sleeping more than the normal amount of 7 to 9 hours per night can also be a symptom of a mental health problem.

Feeling of restlessness or being slowed down: You may feel that you are unable to sit still and must always be up moving. You could also experience feeling shaking or have unusual movements. By contrast, you could also feel slowed down and not able to move as quickly or as graceful as you normally would.

Energy: Along with problems getting the appropriate amount of sleep each night, feelings of not having enough energy to get through the day are also common with many mental health problems. Many patients with depression or anxiety issues complain of feelings of significant fatigue and low energy and are not able to complete things that they either must do or want to do.

Concentration: Many mental health issues can contribute to an individual’s ability to focus and concentrate. You can recognize your ability to concentrate by noticing if your productivity levels have decreased, if you’re unable to make deadlines, or if you’re unable to complete simple daily tasks such as housework. You may also find that you are unable to make appropriate decisions in a timely manner.

Physical symptoms: some mental health illnesses may manifest with physical symptoms such as stomach pain, back pain, headaches, and other general body aches and pain.

Preparing for your first visit.

Experiencing even just a few of these signs and symptoms is a reason to see your doctor or a mental health provider, especially if they are interfering with your ability to function on a day-to-day basis. You may choose to discuss your mental health concerns with your primary care doctor or you may go directly to a mental health provider, such as a psychiatrist or psychologist. In preparation for your first appointment, you should think about a number of questions that your doctor may ask you. These include:

When did you first notice your symptoms?

Has your day-to-day life been affected by your symptoms?

What have you tried to treat your symptoms on your own?  

Do you notice anything that makes you feel worse? Do your symptoms have a specific trigger?

Have your friends or family members commented on your mood?

Does mental illness run in your family?

What do you expect from treatment?

What medications, supplements, or herbs to you currently take?

Do you drink alcohol or use illegal (street) drugs?

It is important for you to think about the types of questions you should ask your doctor or other mental health provider prior to your first appointment. Examples of the types of questions to ask your doctor include:

What type of treatment will I receive?

Will counseling or therapy help?

Are there medications that will help?

How long will it take for my treatment to start working?

Is there anything I can do on my own to help myself?

Do you have any brochures that I can have to read?

Suicide Prevention.

If you feel that you are in a crisis or having thoughts of killing yourself please call the Suicide Prevention Lifeline at 1-800-273-TALK (1-800-273-8255) immediately. The Suicide Prevention Lifeline is a 24-hour service available to anyone in need of help.

Where to find more information.

If you would like to find out more about mental health or mental illness, below are a few helpful resources:

American Psychological Association: http://www.apa.org/

National Institute of Mental Health: http://www.nimh.nih.gov/index.shtml

American Psychiatric Association: http://www.psychiatry.org/mental-health

Mental Health America: http://www.mentalhealthamerica.net/

National Alliance on Mental Illness: http://www.nami.org/

Maggie Thomas

Doctor of Pharmacy Candidate

College of Pharmacy, University of Illinois at Chicago

UIC Pharmacy

November 2013

References

1.     What is mental health? U.S. Department of Health and Human Services.http://www.mentalhealth.gov/basics/what-is-mental-health/index.html. Accessed November 12, 2013.

2.     Mental health. National Institute of Mental Health.http://www.nimh.nih.gov/health/publications/depression/index.shtml. Accessed November 12, 2013.

3.     Warning signs of mental illness. American Psychiatric Association.http://www.psychiatry.org/mental-health/more-topics/warning-signs-of-mental-illness.Accessed November 12, 2013.

Irritable Bowel Syndrome Awareness Month

Irritable bowel syndrome (IBS)
Stan Nikitin

April is IBS month, and you may be wondering “what exactly is IBS?” IBS stands for irritable bowel syndrome, which is a disorder affecting the large intestine, also called the colon.  It's one of the most commonly diagnosed gastrointestinal conditions, affecting 55 million Americans.  This means about 1 in 6 people have symptoms of IBS!  Women tend to be affected more often than men. The exact cause of IBS is unknown. There are many hypotheses and the causes may include genetics, problems with the intestinal muscles, infections, stress or other psychological factors.^1-3

Symptoms of IBS
The symptoms of IBS usually begin in adolescence or early adulthood, but can occur at any age.  Symptoms can vary in severity, but the good news is that most people with IBS have mild symptoms. Abdominal pain, fullness, flatulence (gas), and bloating that have been present for at least 6 months are the main symptoms of IBS.²  While different people are affected differently, the symptoms can also include:

·       Cramping - pain or tightness in the abdomen

·       Changes in bowel movements

·       Constipation or diarrhea - both can occur, but mostly it is one or the other

·       Mucus in the stool⁴

Symptoms are more likely to occur after meals, can come and go, and may be milder or disappear completely following a bowel movement.

All people are affected differently. For most people IBS is a chronic condition, but symptoms can come and go, improve or worsen, and be present constantly or intermittently.

The symptoms of IBS may seem daunting and scary, but fortunately, do not cause any permanent damage to the colon. For example, IBS does not increase the risk for colorectal cancer. Also, IBS does not cause any inflammation or changes in bowel tissue unlike the more serious intestinal diseases such as Crohn’s disease or ulcerative colitis.⁴


DiagnosisIBS is largely diagnosed based on symptoms.  Your doctor will diagnose IBS based on your symptoms, medical history, and a physical exam.  If any tests are necessary, they are to rule out any other conditions.  The tests may be necessary especially if there is weight loss, rectal bleeding, fever, nausea or recurrent vomiting, abdominal pain that is not completely relieved by a bowel movement, diarrhea that is persistent or awakens you from sleep, or if symptom onset occurs after the age of 50.  Some of the tests can include:⁴

·       Blood tests - check for blood loss or deficiency, inflammation, and Celiac disease (symptoms of which may resemble IBS)

·       Stool analysis - checks for blood in the stool and certain infections (for example, parasites).

·       Sigmoidoscopy or colonoscopy - allows the doctor to look inside the intestine for abnormal growths, bleeding, inflammation, and other irregularities

·       Lactose intolerance test - tests for lactase deficiency. Some people lack the enzyme lactase, which breaks down dairy sugars. Affected people may have symptoms resembling IBS after eating or drinking dairy products. Your doctor may instruct you to avoid dairy products for several weeks to rule out lactase deficiency.

TreatmentWhile IBS is a chronic condition, it is manageable. The focus of treatment is to relieve symptoms. Diet and lifestyle changes can help you manage IBS. More severe forms of IBS may require the use of medications that can help alleviate symptoms.


Diet and Lifestyle ChangesMaking changes to your diet and lifestyle may help relieve IBS symptoms.

Lifestyle changes:

·       Exercise - exercise may reduce anxiety and stress, which in turn may help relieve IBS symptoms.

·       Improved sleep habits – an erratic sleep schedule may worsen IBS symptoms. Improving your sleep habits may help. Try to go to bed at the same time each day and get plenty of sleep to avoid fatigue and potential stress.

Dietary changes:

·       Eat at regular times - try to eat at the same time each day. Do not skip meals. Avoid large meals.

·       Avoid problem foods - avoid foods that you know for certain trigger your IBS symptoms. Avoid fatty foods or ones with high sugar content. Artificial sweeteners (such as sorbitol and mannitol) may be found in sugar-free gum or other foods and can be problematic. Certain foods and drinks stimulate the intestines. Caffeine containing products (coffee, tea, and energy drinks) are notorious for this effect. Carbonated drinks like soda can produce gas. Some other problem foods may include whole grains, chocolate, or alcohol. Vegetables like broccoli, cauliflower, cabbage, and beans can increase gas. Dairy products may cause much discomfort to lactose intolerant people. See lactose intolerance test above.^1,2,4

·       Foods rich in fiber - while fiber-rich foods such as fruits, vegetables, and beans may help with constipation for some people, they can make symptoms worse for others.

·       Drink plenty of water - water is always best. Remember that coffee, tea, alcohol, soda, and dairy products like milk can worsen the symptoms.

MedicationMedication use in IBS should target your most upsetting symptoms. The lowest dose possible that relieves your symptoms is usually recommended. If you are considering using over-the-counter medication, discuss such use with your doctor or pharmacist before selecting one. Explaining your symptoms to your doctor or pharmacist can help the healthcare professional recommend the right medication for you.

Over-the-counter (OTC) medications

·       Immodium (loperamide) - loperamide decreases the frequency of bowel movements, which may be of relief to some with diarrhea, but it does not help with other IBS symptoms.

·       Fiber supplements - fiber supplements such as Metamucil may help with constipation- predominant IBS, but can make symptoms worse for people with diarrhea-predominant IBS.

·       Laxatives - there are various laxative types that work in different ways to help with constipation.  Discuss with your doctor or pharmacist which laxative may be appropriate for you.

Prescription medications

Diarrhea-Predominant IBS:

·       Antispasmodic drugs may help with intestinal spasms and cramping.^2-5 These drugs relax the smooth muscles of the intestine using an anticholinergic mechanism. Some examples of these medications are hyoscyamine and dicyclomine.  Common side effects are drowsiness, dry mouth, blurred vision, constipation, and urinary retention.⁶

·       Cholestyramine may be helpful to people with bile acid absorption problems.^1,3  The mostcommon side effect reported with cholestyramine use is constipation.⁶

·       Lotronex (alosetron) is approved for women only with diarrhea-predominant IBS and has restricted use. It can only be prescribed by a doctor enrolled in a special program.^1,4,5  The most common side effect reported is constipation.⁶

Constipation Predominant IBS:

·       Amitiza (lubiprostone) is approved for women 18 and older only who have constipation predominant IBS. ^{4, 5} Common side effects are nausea, headache, and diarrhea.⁶

Other therapies:

·       Xifaxan (rifaximin) is an oral non-absorbable (acts in the gastrointestinal tract without getting into the bloodstream) antibiotic that may be effective for global IBS symptoms, especially for diarrhea-predominant IBS. ⁷ This drug is minimally absorbed and stays in the intestine. Common side effects are flatulence (gas), nausea, dizziness, and fatigue.⁶

·       For difficult to treat conditions your doctor may prescribe antidepressants. These can include 2 drug classes: tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs). These can be helpful in relieving abdominal pain and slowing down intestinal transit time.^1,2,4,5 Common side effects with TCAs are drowsiness, dry mouth, blurred vision, constipation, urinary retention, and weight gain.⁶  Common side effects with SSRIs are headache, sleepiness, insomnia, nausea, diarrhea, and sexual dysfunction.⁶

·       Other treatment options exist such as probiotics, peppermint oil, herbal therapies and acupuncture. While these treatments may be helpful and beneficial to some, there’s little medical evidence about their effectiveness.

What to expectIrritable bowel syndrome can be a chronic, lifelong condition and has no known cure. Many people with IBS learn to manage the condition and still lead active, fruitful lives. Understandably, the condition may not be easy to discuss, but be open about your communication with healthcare professionals. Be informed, ask lots of questions, and remember that healthcare professionals are there to help! Be your own advocate and take charge in the management of your IBS!

For more information:

·       Mayo Clinic 
http://www.mayoclinic.com/health/irritable-bowel-syndrome/DS00106

·       WebMD
http://www.webmd.com/ibs/default.htm

·       WebMD Support Group Message Board
http://exchanges.webmd.com/ibs-support-group

·       National Institutes of Health
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001292

·       U.S. National Library of Medicine Interactive Tutorialhttp://www.nlm.nih.gov/medlineplus/tutorials/irritablebowelsyndrome/htm/index.htm

·       National Digestive Diseases Information Clearinghouse http://digestive.niddk.nih.gov/ddiseases/pubs/ibs/

·       American College of Gastroenterology
http://www.acg.gi.org/patients/ibsrelief/index.asp

References
1. Spruill WJ, Wade WE. Diarrhea, constipation, and irritable bowel syndrome. In: DiPiro JT, Talbert RL, Yee G, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach. 7th ed. New York, NY: McGraw-Hill; 2008:628-631.2. U.S. National Library of Medicine, National Institutes of Health. Irritable bowel syndrome. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001292. Updated July 7, 2010. Accessed February 24, 2011.

3. WebMD. Irritable bowel syndrome health center. http://www.webmd.com/ibs/default.htm. Updated May 23, 2008. Accessed February 24, 2011.

4. Mayo Clinic. Irritable bowel syndrome. http://www.mayoclinic.com/health/irritable-bowel-syndrome/DS00106. Updated July 29, 2009. Accessed February 24, 2011.

5. Wald, A. Treatment of irritable bowel syndrome. In: UpToDate, Talley NJ (Ed), UpToDate, Waltham, MA, 2011. Accessed February 24, 2011.6. Wickersham RM, ed. Drug Facts and Comparisons. St. Louis, MO: Wolters Kluwer Health; 2011. http://online.factsandcomparisons.com. Accessed March 2, 2011.

7. American College of Gastroenterology. ACG releases evidence-based systematic review on management of irritable bowel syndrome. http://www.acg.gi.org/media/releases/december182008.asp. Published December 18, 2008. Accessed March 14, 2011.

Party Safe this New Year's Eve

2016 is upon us, time to ring in the New Year! Most of us with gather with family and friends to say goodbye to 2015 and hello to 2016 and that starts with a safe New Year's Eve celebration. So we've compiled safety tips for you to follow and Happy New Year to You and your family from all of us at UI Health Pharmacy!

Heading to a bar or event?

• Be mindful of your surroundings and how others are acting, and give a wide berth to those who seem out of control.
• If someone appears intoxicated, keep them from driving and call them a cab to ensure they get home safely, and don’t let them leave with someone they do not know.
• Locate all the exits when you get there just in-case you need to exit quickly.
• Don't leave an open drink on the bar when you go to washroom or dance floor, have a friend watch it or take it with you.

Heading to house party?

• If you drink, don't drive.
• Plan ahead and always designate a sober driver before the party or celebration begins.
• Stay hydrated by alternating alcoholic drinks with water, juice, or soda.
• If you are impaired, call a taxi, use mass transit, or get a sober friend or family member to come pick you up.
• Or, stay where you are until you are sober.
• Take the keys from someone if you think he/she is too impaired to drive.
• Remember “buzzed” driving is “drunk” driving!

Hosting a party at your place?

• Plan ahead by naming a "designated driver." Make this your responsibility as the host.
• Contact a local cab company to provide rides for your guests.
• Serve non-alcoholic beverages as an option to your guests.
• Stop serving alcohol to your guests several hours before the party ends.
• Provide your guests with a place to stay overnight in your home.
• Don't forget about your pets. They are just as much a part of the family as everyone else. If you are using fireworks, anything with loud noises, or fire, be sure that pets are kept at a distance as well as children. None of these are a good mix!

Hope these tips help and Happy New Year!!

International GERD Awareness Week 2015

International GERD Awareness Week

Gastroesophageal Reflux Disease (GERD)

November 23st through November 29th has been designated International GERD Awareness Week for 2015. An estimated 25 million adults experience heartburn daily, and over 38 million annual outpatient visits are related to this disease.1 You may have heard of GERD, or Gastroesophageal Reflux Disease, most likely in association with heartburn, but what is it exactly? The most common definition of GERD identifies it as the symptoms and damage associated with chronic and recurring abnormal backward flow (reflux) of the contents of the stomach into the esophagus. The burning sensation that the reflux can sometimes cause is what is typically referred to as heartburn. While usually not life-threatening, GERD has a significantly negative impact on the quality of life of those living with this condition. In addition, complications of GERD range from erosion of the cells in the esophageal lining to adenocarcinoma (a type of cancer).

What causes GERD?

Between the esophagus and stomach lies a sphincter, or valve, that opens in order for food to pass into the stomach.2 Improper function of this valve allows for the reflux to occur, and can happen for 3 different reasons: (1) the sphincter relaxes at the wrong time, (2) the sphincter weakens, or (3) the pressure in the abdomen is increased. While the cells lining the stomach are protected against its strong acidity, the cells lining the esophagus are not. When frequently exposed to the stomach contents, these cells can become inflamed and even erode in some instances.

Who has GERD?

The disease can occur at any age, but is commonly seen in those over 40. 2 In general, there is no significant difference in its prevalence between men and women, although pregnant women frequently experience GERD due to hormonal changes and increase in abdominal pressure. Those with asthma, diabetes, peptic ulcers, or obesity are also more likely to have GERD. 3 However, the prevalence of the disease is hard to assess for 2 reasons, the first being that there is no gold standard in diagnosing the disease, and second, many patients do not seek medical treatment for their symptoms.1,2

The lack of set criteria for diagnosing the disease makes it hard to characterize and distinguish from other problems such as ulcers and cancer. 4 Therefore, many factors are considered before a diagnosis of GERD is made, including patient family history, an endoscopy to check the lining of the esophagus, or a short trial of certain medications called proton-pump inhibitors (PPIs).

What are the symptoms of GERD?

Like previously stated, heartburn is the most commonly experienced symptom, however others include sore throat, hoarseness, chronic cough, asthma, chest pain, and a sensation of a lump in the throat. It should be noted that while occasional heartburn is fairly common in a healthy population, those with GERD experience it on a much more frequent basis. 

Foods and medications can worsen GERD symptoms

Certain foods and drugs can worsen the symptoms of GERD either by lowering the esophageal sphincter pressure, making it easier to open, or by directly irritating the lining of the esophagus. A list of these foods and medications can be found in Tables 1 and 2, respectively.  

Table 1: Foods that Worsen GERD Symptoms2,4
Decrease Lower Esophageal Sphincter Pressure	·      Onions ·      Garlic ·      Chili Peppers ·      Fatty Meals ·      Carminatives – Peppermint, spearmint ·      Chocolate ·      Coffee, colas, tea
Direct Irritants to Esophageal Lining	·      Spicy Foods ·      Tomato Juice ·      Coffee ·      Orange Juice

Table 2: Medications that CanWorsen GERD Symptoms2
Decrease Lower Esophageal Sphincter Pressure	·      Ethanol ·      Nicotine ·      Caffeine ·      Anticholinergics – group of medications that can affect the transmission of nerve impulses to the gastrointestinal tract, urinary tract, lungs, etc ·      Nitrates – used to treat angina ·      Dihydropyridine calcium channel blockers – used to treat high blood pressure ·      Tetracycline – an antibiotic ·      Theophylline – used to treat asthma and other lung disease
Direct Irritants to Esophageal Lining	·      Iron ·      Potassium ·      Alendronate – for the treatment and prevention of osteoporosis ·      Nonsteroidal anti-inflammatory drugs – pain medications such as  ibuprofen, aspirin,

How is GERD treated?

It is essential to talk to your physician before starting any therapy for GERD, to find out if you are a candidate for self treatment or if you should be under their supervision.^4,5 Certain symptoms such as hoarseness, coughing, weight loss, vomiting, and chest pain are some of the more alarming ones that would warrant physician assisted care. Also, conditions like pregnancy and age younger than 16 or older than 50, should be under a provider’s care when initiating any medications.

Goals of therapy¹
The goals for the treatment of GERD are to:

·      Alleviate or eliminate symptoms

·      Decrease the frequency, recurrence, and duration of GERD

·      Heal any injured esophageal lining

·      Prevent complications

Lifestyle Modifications ^2,3,4

This is usually the first approach to treatment of symptoms of GERD. Some lifestyle modifications include:

·      Elevating the head while sleeping

·      Dietary changes

o   Avoiding foods that can aggravate condition

o   Eating protein rich meals (this helps with esophageal sphincter pressure)

o   Eating small meals

o   Avoid eating 3 hours prior to sleep

·      Reduction in weight

·      Smoking cessation

·      Avoiding alcohol

·      Avoiding tight fitting clothes

·      If possible, discontinuing drugs that aggravate symptoms (always double check with your physician first).

Medications ^1,2,4
Over-the-counter and prescription drugs are available to help treat the symptoms of GERD. The most basic medications are antacids, which work by lowering the acidity of the gastric juices; they are fast acting and fairly harmless. Histamine type-2 receptor agonists (H­₂ antagonist) drugs are relatively effective in alleviating heartburn, and work by decreasing gastric acid production; all are available over the counter. PPI drugs work to reduce gastric acid production over a long period of time and have been found to be somewhat more effective than H­₂ antagonists in treating heartburn. A list of drugs can be found in Table 3.

 

Table 3: Medications Used to Treat GERD1,4,6,7
Drug Class	Drug Name (generic name)	Common Side Effects	Patient Informationa
Antacids	Tums, Rolaids, Gaviscon (Calcium Carbonate)	∙  Stomach upset	∙  Can be used as needed ∙  Have fast onset of action ∙  Should be separated from certain medications by 2 to 4 hours to avoid drug interactions. Discuss with your pharmacist for more information.
H2 Antagonists	Zantac (ranitidine)	∙  headache ∙  constipation ∙  diarrhea ∙  nausea ∙  vomiting ∙  stomach pain ∙  dizziness ∙  rash ∙  breast enlargementc	∙  Patients should contact their prescriber if symptoms persist and they have to use these medications for more than 14 days. ∙  Talk to your doctor if pregnant or breastfeeding. ∙  It is advisable to take these medications a half hour to one hour before a meal. ∙  If planning on taking cimetidine, patients should talk to their prescribers if already on theophylline, warfarin, and phenytoin (these medications interact with cimetidine).
	Pepcid (famotidine)
	Tagamet (cimetidine)b
	Axid (nizatidine)
Proton-Pump Inhibitors	Prilosec (omeprazole)	∙  stomach pain ∙  diarrhea ∙  headache ∙  nausea ∙  constipation ∙  bloating ∙  flatulence	∙  Take half hour to an hour before a meal. ∙  Contact your doctor if you experience any of the side effects.
	Nexium (esomeprazole)
	Protonix (pantoprazole)
	Aciphex (rabeprazole)
	Prevacid (lansoprazole)
	Dexilant (dexlansoprazole)

^a Before starting any medication, be sure to check with your doctor or pharmacist about whether any of them interact with medications you are currently taking; ^b Caution should be taken when using cimetidine because of its susceptibility to numerous drug interactions; ^c Breast enlargement could be experienced with cimetidine.

 If lifestyle changes and medication fail to alleviate symptoms of GERD, a final option is surgery.¹ Several different procedures can be done, but all focus on strengthening the sphincter and reducing reflux.

Conclusion

GERD is a chronic disease that can severely impact the quality of life for those who suffer from it; severe cases can even develop into cancer. However, implementation of lifestyle modifications, along with different medications can help improve and manage this condition. When treatments fail to work, another viable option is surgery.

For more information on GERD visit these resources:

• American Gastroenterological Association:
  http://www.gastro.org/patient-center/digestive-conditions/heartburn-gerd

• UC San Diego Health System:
   http://health.ucsd.edu/specialties/esophageal-center/GERD.htm

• The Mayo Clinic:
  http://www.mayoclinic.com/health/gerd/DS00967

• International Foundation for Functional Gastrointestinal Disorders:
  1-888-964-2001

Written by:

Asha Kalichira, PharmD Student 2014

Milena Babic, PharmD Candidate 2011

References:

1. University of Michigan Health System, Ann Arbor, MI. Gastroesophageal Reflux Disease.  http://cme.med.umich.edu/pdf/guideline/GERD07.pdf.  Updated January 2007. Accessed October 27, 2010.

2. Williams DB, Schade RR. Gastroesophogeal reflux disease. In: DiPiro JT, Talbert RL, Yee G, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach. 7th ed. New York, NY: McGraw-Hill; 2008: 555-567.

 

3. UC San Diego Health System. Gastroesophageal Reflux (GERD).                  http://health.ucsd.edu/specialties/esophageal-center/GERD.htm. Accessed October 27,      2010.

 

4. Kahrilas PJ, Shaheen NJ, Vaezi MF. American Gastroenterological Association medical position statement on the management of gastroesophageal reflux disease. Gastroenterology. 2008;135(4):1383-1391.

5. Henderson RP, Prince VT. Heartburn and dyspepsia. In: Berardi RR, McDermott JH, Newton GD, Oszko MA, Popovich NG, Rollins CJ, Shimp LA, Tietze KJ, eds. Handbook of Nonprescription Drugs. 14^th ed. Washington, DC: American Pharmacist Association; 2004: 317-348.

6. Micromedex® Healthcare Series [Internet database]. Greenwood Village, CO: Thomson Reuters (Healthcare) Inc. Updated periodically.

7. Kastrup EK,ed. Drug Facts and Comparisons. St. Louis: MO; Wolters Kluwer Health; 2010.